The use of medical
disinfectants help to prevent the spread of harmful bacteria and
viruses and promote disinfection in
hospitals. Many infectious diseases can be halted in their tracks by the use of proper hospital hygiene products. Infectious diseases such as tuberculosis, mucormycosis
(a flesh-eating fungal infection) are mostly caused by pathogens including
bacteria, fungi and viruses. Health care-associated infections, or HAIs, are
infections that patients acquire while they are receiving treatment for another
condition in a healthcare setting. Reusable medical devices such as surgical
instruments and endoscopes can also harbor pathogens and be responsible for
HAIs.
The main
disease causing microbes are viruses, bacteria and fungi. They are all beyond
normal human eye vision but still they are potential disease
causing agents. Disinfectants
are thus extensively used in hospitals and other health care settings and are
called as hospital grade
disinfectants for a variety
of topical and hard-surface applications.
A
wide variety of active chemical agents (biocides) are used as disinfectants, including alcohols,
phenols, iodine, and chlorine etc.
Ethyl alcohol,
isopropyl alcohol and n-propanol are the most widely used alcohols
against microbial activity. Alcohols exhibit rapid broad-spectrum antimicrobial
activity against vegetative bacteria (including mycobacteria), viruses, and
fungi. Among aldehydes glutaraldehyde is an important dialdehyde that has found
usage as a disinfectant and sterilant, in particular for low-temperature
disinfection and sterilization of endoscopes and surgical equipment and as a
fixative in electron icroscopy. Glutaraldehyde has a broad spectrum of activity
against bacteria and their spores, fungi, and viruses. Ortho-phthaladehyde
has t microbiocidal activity and mycobactericidal activity and has potent
bactericidal and sporicidal activity. Like glutaraldehyde, it interacts with
amino acids, proteins and microorganisms.Formaldehyde-primarily available as a water based solution called
formalin, which contains 37% formaldehyde by weight is used as a high level
disinfectant. Formaldehyde has been traditionally used to sterilize equipment such as
surgical instruments and haemodialysers in combination with alcohols.
Paraformaldehyde, a solid polymer of formaldehyde, is used in combination with
low-temperature steam for the disinfection of heat-sensitive medical equipment.
Peracetic acid based solutions are also used as sporicidal, bactericidal,
virucidal and fungicidal at low concentrations. Chlorine- and iodine-based compounds are the most significant
microbicidal halogens used in the clinic and have been traditionally used for disinfectant
purposes. The most important types of CRAs are sodium hypochlorite, chlorine
dioxide, and the N-chloro compounds such as sodium
dichloroisocyanurate (NaDCC), with chloramine-T being used to some extent. Iodine
, although less reactive than chlorine,
is extensively used as bactericidal, fungicidal, tuberculocidal,
virucidal, and sporicidal agents in medical disinfectants. Disinfectant
solutions containing 7.5% hydrogen peroxide are used for sterilisation and high-level disinfection in
healthcare Quaternary
ammonium compounds have also been used
against microbial activity in hospitals.Many phenolic
compounds also possess antifungal and
antiviral properties. Their antifungal action probably involves damage to the
plasma membrane resulting in leakage of intracellular constituents. Thus
phenols have also found its application in hospital disinfectant products.
These
disinfectants which are extensively used in hospitals have found to cause many
adverse effects. Formaldehyde is known to have carcinogenic effects. Acute or chronic
exposure of glutaraldehyde results in skin irritation, mucous membrane
irritation and multiple pulmonary symptoms such as occupational asthma and
allergic rhinitis. Triclosan,
the active ingredient in most antibacterial products, not only kills bacteria,
it also has been shown to kill human cells Phenol is toxic and people who are
hypersensitive can experience serious side effects at very low levels. Phenols
cause damage to respiratory and circulatory systems. It can seriously affect liver,
kidneys and eyes. Chlorine based compounds emit harmful fumes which makes it
unsuitable to be used as a hospital disinfectant products. Most of these
disinfectants are non biodegradable and
can cause potential environmental hazards.
ALSTASAN
SILVOX, a synergistic blend of hydrogen peroxide with silver ions is
highly effective against microbial activity and can be used extensively as
hospital grade disinfectant. It find
application as disinfectant wipes, floor disinfectant, hospital disinfectant
cleaner, disinfectant spray, disinfectant spray, hospital sanitizer products
etc.
Silver ions show
oligo-dynamic effect on bacterial cells in relatively lower concentrations
compared to the traditional disinfectants. Silver ions denature enzymes by
reacting with the thiol groups to form silver sulfides. Hydrogen peroxide when
used alone as a disinfectant it decomposes to oxygen and water. Silver when
added to hydrogen peroxide prevents its slow decomposition.
The silver performs as an
activator, but it activates the peroxide only when it is exposed to
bio-foulants. On coming in contact with microbials the silver loses its
stabilizing function and activates to release nascent oxygen to oxidize the exposed
microbes. When all bacteria has been oxidized by the generated active oxygen
compounds, the silver once again acts as a stabilizer for the remaining and non
reacted oxygen.
SILVOX use as a medical
disinfectant dominates other commercial disinfectants products because of its
unique features. It does not require heat for disinfection and thus can act as
a cold sterilant. Unlike others it is effective at a very low concentration
over a large range of micro-organisms and destroys biofilm. When used as a
floor disinfectant it does not leave any stains on floor. Its non foaming
nature makes it suitable for spraying, fogging and fumigation. .It does not leave
back any odor in the rooms so can be used effectively as a hospital
disinfectant cleaner.
It is completely
organic in nature and does not leave any toxic residue and does not emit any
harmful fumes, Alstasan Silvox is biodegradable and has no adverse effect on
environment.
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